Ipamorelin is a synthetic pentapeptide that functions as a ghrelin receptor (GHSR-1a) agonist, stimulating the release of growth hormone (GH) from the anterior pituitary. It is part of the GHRP (growth hormone-releasing peptide) family but is distinguished by its high selectivity and minimal impact on other pituitary hormones such as cortisol and prolactin.

Research has focused on Ipamorelin’s role in promoting anabolic activity, including protein synthesis, muscle growth, and tissue repair, as well as its influence on fat metabolism. Its selective action on GH release without broad endocrine disruption makes it a valuable compound in studies related to anti-aging, musculoskeletal recovery, and metabolic health.

Additionally, Ipamorelin’s favorable safety profile and minimal side effects have made it a candidate for long-term studies examining the physiological effects of pulsatile GH elevation, particularly in contexts where restoring natural hormonal rhythms is desired.